Wikipedia writes: 'Myricetin is a member of the flavonoid class of polyphenolic compounds, with antioxidant properties. It is commonly derived from vegetables, fruits, nuts, berries, tea, and is also found in red wine. Myricetin is structurally similar to fisetin, luteolin, and quercetin and is reported to have many of the same functions as these other members of the flavonol class of flavonoids.' (link #1 at the end of this article.)
Note. Please be sure to read the important medical disclaimer at the bottom of this page.
Myricetin research links.
The US National Library of Medicine (link below) has a research summary from the College of Natural Sciences, South Korea, The researcher writes: 'Previous studies have demonstrated that myricetin has anticancer effects against several types of cancer, including hepatocarcinoma, skin carcinoma, and pancreatic cancer. However, the anticancer activity of myricetin on human colon cancer has not been yet established. In the present study, we investigated the anticancer effects of myricetin on HCT-15 human colon cancer cells. We found that myricetin induces cytotoxicity and DNA condensation in human colon cancer cells in a dose-dependent manner. We also determined that myricetin increases the BCL2-associated X protein/B-cell lymphoma 2 ratio, but not cleavage of caspase-3 and -9. In addition, myricetin induced the release of apoptosis-inducing factor from mitochondria. These results suggest that myricetin induces apoptosis of HCT-15 human colon cancer cells and may prove useful in the development of therapeutic agents for human colon cancer.' (link #2)
In another research summary titled 'The red wine phenolics piceatannol and myricetin act as agonists for estrogen receptor alpha in human breast cancer cells', the US National Library of Medicine write: 'Previous epidemiological reports have suggested that red wine intake is associated with beneficial health effects due to the ability of certain phytochemical components to exert estrogen-like activity. It has been also documented that estrogens induce the proliferation of hormone-dependent breast cancer cells by binding to and transactivating estrogen receptor (ER) alpha, which in turn interacts with responsive DNA sequences located within the promoter region of target genes. (Some technical text removed here for this ebook. Please go to the website for the full story.) In summary, the researchers write: 'Hence, the estrogenic activity of PIC (piceatannol) and MYR (myricetin) might be considered at least as a potential factor in the association of red wine intake and breast tumors, particularly in postmenopausal women.' (link #3)
The consumer website 'Before It's News' lists 14 possible benefits of myricetin, and also includes links to relevant research papers. (link #4)
In an independent laboratory test by The University of Georgia, muscadine grapes (esp the skin) were found to have between 0.7 and 6.3 milligrams of myricetin per 100 grams (3.5 ounces) of fresh fruit. (link #5)
Wikipedia. About Myricetin.
US National Library of Medicine. Myricetin induces cell death of human colon cancer cells via BAX/BCL2-dependent pathway.
US National Library of Medicine. The red wine phenolics piceatannol and myricetin act as agonists for estrogen receptor alpha in human breast cancer cells.
Before It's News. 14 Health Benefits of Myricetin.
US National Library of Medicine. Phenolic content and antioxidant capacity of muscadine grapes.
Medical disclaimer and alert. The information in this webpage is meant to supplement, not replace advice from your doctor or healthcare provider, and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on this page or the pages it links to. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. These statements have not been evaluated by the Food and Drug Administration. Muscadinex, like any other natural health supplement, is not intended to diagnose, treat, cure, or prevent any disease.